David Blossom was born in Chicago, Illinois but lived most of his life on the east coast, growing up in Rye, New York and Weston, Connecticut. He lived in Westport and Southport, Connecticut until 1963, when he moved with his family to Weston, where he lived until his death in 1995.
He worked at Young & Rubicam as an art director (for the Ford Motor Company and Pan American Airways accounts) until moving to Weston, CT when he became a freelance illustrator. He created romance paperback book covers and Western themes (later in his career) and is also known for his movie posters (early Clint Eastwood spaghetti westerns, "The Good, The Bad, and The Ugly", "A Fistful of Dollars", and "A few Dollars More" among others) and magazine covers.